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Appearance:powder
Throughput:100|Kilogram|Month
pd_productuse:intermediate
Delivery Time:in stock
Purity:98% purity
Melting point 182.5-184°
storage temp. Inert atmosphere,2-8°C
form neat
Water Solubility It is very soluble in water, easily soluble in ethyl alcohol, slightly soluble in dichloromethane.
Sensitive Light Sensitive
InChIKey RVFUNJWWXKCWNS-UHFFFAOYSA-N
CAS DataBase Reference 54143-57-6(CAS DataBase Reference)
Safety Information
WGK Germany 3
HS Code 2924296000
Originator Primperan,Delagrange,France,1964
Uses Dopamine receptor antagonist; antiemetic.
Indications Metoclopramide (Reglan) stimulates upper GI tract motility and has both central and peripheral actions. Centrally, it is a dopamine antagonist, an action that is important both for its often desirable antiemetic effect and other less desirable effects. Peripherally, it stimulates the release of intrinsic postganglionic stores of acetylcholine and sensitizes the gastric smooth muscle to muscarinic stimulation. The ability of metoclopramide to antagonize the inhibitory neurotransmitter effect of dopamine on the GI tract results in increased gastric contraction and enhanced gastric emptying and small bowel transit.
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