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Appearance:powder
Throughput:100|Kilogram|Day
pd_productuse:intermediate
Delivery Time:in stock
Purity:97% purity
Melting point 106-109 °C (lit.)
Boiling point 354.0±15.0 °C(Predicted)
density 1.268±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka 18.23±0.30(Predicted)
Water Solubility Insoluble
Sensitive Air Sensitive
BRN 114919
CAS DataBase Reference 5192-23-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25
WGK Germany 3
F 8-10-34
HazardClass AIR SENSITIVE, IRRITANT-HARMFUL, KEEP COLD
HS Code 29339990
MSDS Information
Provider Language
4-Aminoindole English
SigmaAldrich English
ACROS English
ALFA English
4-Aminoindole Usage And Synthesis
Chemical Properties Greenish-grey to tan powder
Uses Reactant for preparation of:• ;Inhibitors of bacterial thymidylate synthase1• ;Mimetics of non-alkaloid toxin lignan anticancer and antiviral agent Podophyllotoxin (PPT)2• ;Inhibitors of Gli1-mediated transcription in the Hedgehog pathway3• ;Protein kinase C θ (PKCθ) inhibitors4• ;Indolic non-peptidic HIV protease inhibitors5• ;Transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists6• ;Cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors7• ;11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibi
Synthesis Reference(s) The Journal of Organic Chemistry, 48, p. 5130, 1983 DOI: 10.1021/jo00173a071
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