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108-75-8

Product Name:2,4,6-Collidine
Molecular Formula:C₈H₁₁N
Appearance:colourless liquid

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Product Details

Appearance:colourless liquid

Purity:99%

Export High Purity 2,4,6-Collidine 108-75-8

108-75-8 Name
Name	2,4,6-Collidine
Synonym	2,4,6-Kollidin;2,4,6-trimethyl-pyridin;a,g,a'-Collidine;alpha,gamma,alpha’-collidine;alpha,gamma,alpha'-Collidine;g-Collidine;Pyridine,2,4,6-trimethyl-;2 Minus 2-3 Methyl pyridine

108-75-8 Chemical & Physical Properties
Melting point	−43 °C(lit.)
Boiling point	171.0±9.0 °C at 760 mmHg
Density	0.9±0.1 g/cm3
Molecular Formula	C8H11N
Molecular Weight	121.180
Flash Point	57.2±0.0 °C
PSA	12.89000
LogP	2.11
Exact Mass	121.089149
Vapour Pressure	1.9±0.3 mmHg at 25°C
Index of Refraction	1.502
Storage condition	2-8°C
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
Water Solubility	35 g/L (20 ºC)

High Purity 2,4,6-Collidine 108-75-8 Usage

2,4,6-Trimethylpyridine is a pyridine derivative. It has a pK of 7.4. The product can react with trifluoroiodomethane in cyclopentane solution to afford 1:1 complex. 2,4,6-collidine can used as monomer to produce a series of highly crystalline olefin-linked COFs by a melt polymerization method. This complex was investigated by NMR (Nuclear Magnetic Resonance) spectroscopy. 2,4,6-Collidine is used as a tissue fixative for electron microscopy. It is useful in dehydrohalogenation reactions and acts as a solvent for the cleavage of hindered esters by anhydrous lithium iodide. The crystal structure of 2,4,6-collidine (2,4,6-trimethylpyridine, C8H11N) has been determined at 180 (2) K following in situ crystal growth from the liquid.

Definition

Methyl, ethyl, propyl, and trimethyl homologs of pyridine.

InChI:InChI=1/C8H11N/c1-6-4-7(2)9-8(3)5-6/h4-5H,1-3H3

108-75-8 Relevant articles

Association of Pyramidal Boron Lewis Superacids with Pyridines: Bending 2, 4, 6‐Collidine with the 10‐Sulfonium‐9‐boratriptycene

Arnaud Osi, Nicolas Niessen, Damien Mahaut, Prof. Benoît Champagne, Dr. Aurélien Chardon, Dr. Nikolay Tumanov, Prof. Johan Wouters, Prof. Guillaume Berionni

ZAAC, Early View Online Version of Record before inclusion in an issue e202300009

The association of pyridine and of 2,4,6-trimethylpyridine (collidine) with a pyramidal triarylborane belonging to the 9-boratriptycene family is investigated by NMR spectroscopy and by X-ray diffraction analysis. Despite of the large size of the ortho-disubstituted collidine Lewis base and of the large steric hindrance of the boron Lewis superacid used (9-boratriptycene-10-sulfonium), the superacidity at its boron atom is enabling the formation of a B-N bond and is resulting in a very stabe Lewis adduct.

New stable atropisomers derived from 2, 4, 6-collidine and related compounds

Joanna Szawkało , Dariusz Błachut , Piotr Roszkowski , Piotr Pomarański , Jan K. Maurin , Armand Budzianowski , Zbigniew Czarnocki

Tetrahedron Volume 72, Issue 43, 27 October 2016, Pages 6779-6787

In this report we describe further extension of the research on other derivatives of 3,5-diaryl substituted 2,4-, 2,6-lutidines and 2,4,6-collidines. In summary, we prepared a library of compounds using the Suzuki–Miyaura cross-coupling reaction between 3,5-dibromo-2,4,6-collidine and bromo derivatives of 2,6- and 2,4-lutidine with a series of ortho-substituted boronic acids.