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Appearance:White to yellow crystalline solid
Throughput:100|Kilogram|Month
pd_productuse:API
Delivery Time:large stock
Purity:99% purity
Nadifloxacin Chemical Properties
Melting point 245-2470C (dec)
Boiling point 624.9±55.0 °C(Predicted)
density 1.46±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
pka 5.55±0.40(Predicted)
form White to yellow crystalline solid.
Merck 14,6345
CAS DataBase Reference 124858-35-1(CAS DataBase Reference)
Safety Information
Toxicity LD50 male, female mice and rats (mg/kg): 376.5, 420.6, 225.7, 240.5 i.v. (Hashimoto)
Chemical Properties Off-White Crystalline Solid
Originator Otsuka (Japan)
Uses Fluorinated quinolone antibacterial (topical).
Uses Fluorinated quinolone antibacterial (topical)
Uses Calcium salt of polyacrylic acid crosslinked with divinyl glycol
Brand name Acuatim
Pharmaceutical Applications A lipophilic tricyclic fluorobenzoquinoline with a 4- hydroxylpiperinyl moiety at the C-8 position, formulated as a cream for topical use. It is active against many Grampositive bacteria involved in skin infections, including Propionibacterium acnes (MIC 0.25–2.0 mg/L), and Staph. aureus (MIC 0.015–2 mg/L). It appears to inhibit the generation of reactive oxygen species by neutrophils. The sodium salt is used as a 1% cream for use in acne vulgaris and cutaneous staphylococcal infections.
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