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25654-31-3

  • Product Name:Cannabigerol
  • Molecular Formula:C21H32 O2
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Product Details

Purity:99%

Plant Extract Cannabigerol 25654-31-3 Supply

25654-31-3 Name

Name

Cannabigerol

Synonym

 cannabigerol;Cannabigerol (exempt preparation);Cannabigerol solution;2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5-pentylbenzene-1,3-diol;Cannabigerol (CRM);2-[(2E)-3,7-Dimethyl-2,6-octadienyl]-5-pentylresorcinol;2-[(E)-3,7-Dimethyl-2,6-octadienyl]-5-pentyl-1,3-benzenediol;1,3-Benzenediol, 2-[(2E)-3,7-diMethyl-2,6-octadien-1-yl]-5-pentyl-

 

25654-31-3 Chemical & Physical Properties

Melting point 

49-50 °C

Boiling point

470.4±40.0 °C at 760 mmHg

Density

1.0±0.1 g/cm3

Molecular Formula

C21H32O2

Molecular Weight

316.478

Flash Point

 207.2±21.9 °C

PSA

40.46000

LogP

7.47

Exact Mass

316.240234

Vapour Pressure

0.0±1.2 mmHg at 25°C

Index of Refraction

1.536

Storage condition

-20°C

Cannabigerol 25654-31-3 In Medicine

Cannabigerol (CBG) is one of the major phytocannabinoids present in Cannabis sativa L. It is a cannabinoid from the plant Cannabis sativa that lacks psychotomimetic effects. Research on cannabigerol (CBG) mainly due to its low concentration in the Cannabis plant.

InChI:InChI=1/C21H32O2/c1-5-6-7-11-18-14-20(22)19(21(23)15-18)13-12-17(4)10-8-9-16(2)3/h9,12,14-15,22-23H,5-8,10-11,13H2,1-4H3/b17-12+

25654-31-3 Relevant articles

Safety assessment and redox status in rats after chronic exposure to cannabidiol and cannabigerol

Hana Holcova Polanska , Katerina Petrlakova , Barbora Papouskova , Michal Hendrych , Amir Samadian , Jan Storch , Petr Babula , Michal Masarik , Jan Vacek

Toxicology Volume 488, April 2023, 153460

Cannabidiol (CBD) and cannabigerol (CBG) are the two main non-psychotropic phytocannabinoids with high application potential in drug development. In CBG, there is an extra dimethyloctadienyl structural pattern, which is most likely responsible for the disruption to the redox status and hepatic environment. In this study, we focused on in vivo safety evaluation and the effect of CBD and CBG on redox status in rats in a 90-d experiment.

The antinociceptive activity and mechanism of action of cannabigerol

Yuting Wen , Zefeng Wang , Rui Zhang , Yuying Zhu , Guoqiang Lin , Ruixiang Li , Jiange Zhang

Biomedicine & Pharmacotherapy Volume 158, February 2023, 114163

Cannabigerol (CBG) is a nonpsychoactive ingredient that was extracted in the same year with THC . CBG has been suggested as an antinociceptive compound, but the antinociceptive activity of CBG has been evaluated in a few preclinical studies. In this study, we demonstrated the antinociceptive activity of CBG in different pain models and elucidated the mechanism by which CBG targets two receptors, TRPV1 and CB2R, to produce antinociceptive effects.

25654-31-3 Process route

Geraniol
106-24-1

Geraniol

Olivetol
500-66-3

Olivetol

2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5-pentyl-benzene-1,3-diol
25654-31-3,26645-67-0,2808-33-5

2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5-pentyl-benzene-1,3-diol

Conditions
Conditions Yield
With toluene-4-sulfonic acid; In chloroform; at 20 ℃; for 12h; Darkness;
80%
With aluminum oxide; In 1,2-dichloro-ethane; for 6h; Time; Reflux;
62%
With toluene-4-sulfonic acid; In chloroform; at 20 ℃; for 12h; Darkness;
39.9%
With toluene-4-sulfonic acid; In chloroform; at 20 ℃; for 12h; Darkness;
39.9%
With toluene-4-sulfonic acid; In chloroform; at 20 ℃; for 12h; Darkness;
39.9%
With toluene-4-sulfonic acid; In chloroform; at 20 ℃; for 12h; Darkness;
39.9%
With boron trifluoride diethyl etherate; silica gel; In dichloromethane; for 48h; Ambient temperature;
29%
With toluene-4-sulfonic acid; In chloroform; at 20 ℃; for 12h; Darkness;
28%
With toluene-4-sulfonic acid; In chloroform; at 20 ℃; for 14h; Reagent/catalyst; Temperature;
25%
With toluene-4-sulfonic acid; In toluene; at 10 ℃; for 72h; Reagent/catalyst; Temperature; Solvent; Darkness;
13%
With aluminum oxide; In hexane; for 6h; Solvent; Reagent/catalyst; Reflux;
12 %Spectr.
With toluene-4-sulfonic acid; In chloroform; at 20 ℃; for 12h; Solvent; Temperature; Darkness;
1.4 g
(E)-8-(3,7-dimethylocta-2,6-dien-1-yl)-7-hydroxy-2,2-dimethyl-5-pentyl-4H-benzo[d][1,3]dioxin-4-one

(E)-8-(3,7-dimethylocta-2,6-dien-1-yl)-7-hydroxy-2,2-dimethyl-5-pentyl-4H-benzo[d][1,3]dioxin-4-one

2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5-pentyl-benzene-1,3-diol
25654-31-3,26645-67-0,2808-33-5

2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5-pentyl-benzene-1,3-diol

Conditions
Conditions Yield
With water; potassium hydroxide; In 1,4-dioxane; at 120 ℃; for 18h; Sealed tube;
64%

25654-31-3 Upstream products

  • 106-24-1
    106-24-1

    Geraniol

  • 500-66-3
    500-66-3

    Olivetol

  • 63953-93-5
    63953-93-5

    (E)-3-(3,7-dimethylocta-2,6-dien-1-yl)-2,4-dihydroxy-6-pentylbenzoic acid methyl ester

  • 763-10-0
    763-10-0

    geranyl diphosphate

25654-31-3 Downstream products

  • 95543-71-8
    95543-71-8

    2-(3,7-dimethylocta-1,6-dienyl)-5-pentylresorcinol

  • 29106-17-0
    29106-17-0

    cannabigerol monomethyl ether

  • 29106-16-9
    29106-16-9

    1,3-bis(methoxy)cannabigerol

  • 25555-57-1
    25555-57-1

    CBGA

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