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Purity:99%
446-09-3 Name |
|
Name |
1-BROMO-4-FLUORO-2-NITROBENZENE |
Synonym |
1-BROMO-4-FLUORO-2-NITROBENZENE;2-BROMO-5-FLUORONITROBENZENE;1-Bromo-2-nitro-4-fluorobenzene;2-Bromo-5-fluoronitrobenzene 98%;2-Bromo-5-fluoronitrobenzene98%;1-BroMo-4-Fluoro-2-nitrobenzebe;2-BroMo-5-fluoronitrobenzene, 97+%;2-Bromo-5-fluoroanitrobenzene |
446-09-3 Chemical & Physical Properties |
|
Melting point |
37-39°C |
Boiling point |
220.9±20.0 °C at 760 mmHg |
Density |
1.8±0.1 g/cm3 |
Molecular Formula |
C6H3BrFNO2 |
Molecular Weight |
219.996 |
Flash Point |
87.4±21.8 °C |
PSA |
45.82000 |
LogP |
2.41 |
Exact Mass |
218.933105 |
Vapour Pressure |
0.2±0.4 mmHg at 25°C |
Index of Refraction |
1.580 |
1-BROMO-4-FLUORO-2-NITROBENZENE 446-09-3 is light yellow powder.
InChI:InChI=1/C6H3BrFNO2/c7-5-2-1-4(8)3-6(5)9(10)11/h1-3H
The invention discloses a method for preparing 2-bromo-5-fluoroaniline, belonging to the field of organic chemical synthesis. The method has the advantages of high product yield, high purity, easy availability of raw materials and simple operation, andis beneficial to industrial production.
The invention discloses a synthesis method of 2-bromo-5-fluoronitrobenzene and belongs to the field of organic chemistry. A reaction system of the method is simple, raw materials are available, the sulfuric acid aqueous solution can be indiscriminately used many times, the wastewater content is low, and a simple and green approach is provided for the synthesis of the compound.
nitric acid
1-Bromo-4-fluorobenzene
4-bromo-2,6-dinitrophenol
4-Bromo-1-fluoro-2-nitrobenzene
2-bromo-5-fluoronitrobenzene
para-nitrophenyl bromide
Conditions | Yield |
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|
2-nitro-4-fluoroaniline
2-bromo-5-fluoronitrobenzene
Conditions | Yield |
---|---|
2-nitro-4-fluoroaniline; With sulfuric acid; sodium nitrite; In water; at 10 - 20 ℃; Large scale;
With hydrogen bromide; copper(I) bromide; In water; at 40 - 45 ℃; Large scale;
|
79.5% |
With hydrogen bromide; Diazotization.Behandeln der Diazoniumsalz-Loesung mit Kupfer und Bromwasserstoffsaeure;
|
|
|
|
2-nitro-4-fluoroaniline; With hydrogenchloride; sodium nitrite; at 0 ℃;
With hydrogenchloride; copper(I) bromide; at 0 - 60 ℃;
|
2-nitro-4-fluoroaniline
1-Bromo-4-fluorobenzene
nitric acid
4'-fluoroacetanilide
4-fluoro-2-nitro-1,1′-biphenyl
3-(2-Nitro-4-fluor-phenyl)-fluoranthen
7-bromo-4-fluoro-1H-indole
2-bromo-5-fluoroaniline
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