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46113-76-2

  • Product Name:5-butylbenzene-1,3-diol
  • Molecular Formula:C10H14O2
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Product Details

Purity:99%

High Quality 5-butylbenzene-1,3-diol 46113-76-2 Good Supplier

46113-76-2 Name

Name

5-butylbenzene-1,3-diol

Synonym

 5-butylbenzene-1,3-diol;CPDD1006;5-Butyl-1,3-benzenediol;1,3-Benzenediol, 5-butyl-

 

46113-76-2 Chemical & Physical Properties

Melting point 

81.5-82.5 °C

Boiling point

151-152 °C

Density

1.092±0.06 g/cm3(Predicted)

Molecular Formula

C10H14O2

Molecular Weight

166.21700

PSA

40.46000

LogP

2.44040

Exact Mass

166.09900

The chemical formula of  1,3-Benzenediol, 5-butyl- is C10H14O2 which containing 10 Carbon atoms,14 Hydrogen atoms and 2 Oxygen atoms,and the molecular weight of  1,3-Benzenediol, 5-butyl- is 166.22.

 

5-butylbenzene-1,3-diol 46113-76-2 Relevant articles

Analysis of impurities of cannabidiol from hemp. Isolation, characterization and synthesis of cannabidibutol, the novel cannabidiol butyl analog

Cinzia Citti , Pasquale Linciano , Flavio Forni , Maria Angela Vandelli , Giuseppe Gigli , Aldo Laganà , Giuseppe Cannazza

Journal of Pharmaceutical and Biomedical Analysis Volume 175, 25 October 2019, 112752

The latter was prepared by Friedel-Craft allylation of 5-butylbenzene-1,3-diol with (1S,4R)-1-methyl-4-(prop-1-en-2-yl)cycloex-2-enol, using pTSA as catalyst as reported in Scheme 1. …One of the major impurities of CBD extracted from hemp, cannabidibutol (CBDB), was fully characterized for the first time. A stereoselective synthesis was developed in order to confirm its identity and stereochemistry.

Isolation of a High-Affinity Cannabinoid for the Human CB1 Receptor from a Medicinal Cannabis sativa Variety: Δ9-Tetrahydrocannabutol, the Butyl Homologue of Δ9-Tetrahydrocannabinol

Pasquale Linciano, Cinzia Citti, Livio Luongo, Carmela Belardo, Sabatino Maione, Maria Angela Vandelli, Flavio Forni, Giuseppe Gigli, Aldo Laganà, Carmela Maria Montone, and Giuseppe Cannazza

J. Nat. Prod. 2020, 83, 1, 88–98

It was performed initially by direct condensation of 5-butylbenzene-1,3-diol with (1S,4R)-1-… The Friedel-Craft allylation of 5-butylbenzene-1,3-diol with (1S,4R)-1-methyl-4-(prop-1-en-2-…The tetrad test in mice showed a partial agonistic activity of Δ9-THCB toward the CB1 receptor.

46113-76-2 Process route

di-methyl ether of 5-n-butyl-resorcinol
51768-57-1

di-methyl ether of 5-n-butyl-resorcinol

5-n-butyl-1,3-dihydroxybenzene
46113-76-2

5-n-butyl-1,3-dihydroxybenzene

Conditions
Conditions Yield
With boron tribromide; In dichloromethane; at 0 - 20 ℃;
78%
di-methyl ether of 5-n-butyl-resorcinol; With boron tribromide; In dichloromethane; at -15 - 20 ℃; for 2h; Inert atmosphere;
With water; In dichloromethane;
75%
With boron tribromide; In dichloromethane; at 0 - 20 ℃; for 20h; Inert atmosphere;
65%
With hydrogen iodide;
 
With chloro-trimethyl-silane; sodium iodide; In acetonitrile; for 36h; Heating;
 
2,4-dihydroxy-6-n-butylbenzoic acid

2,4-dihydroxy-6-n-butylbenzoic acid

5-n-butyl-1,3-dihydroxybenzene
46113-76-2

5-n-butyl-1,3-dihydroxybenzene

Conditions
Conditions Yield
In methanol; water; at 60 ℃; for 5h;
80%

46113-76-2 Upstream products

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46113-76-2 Downstream products

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