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Purity:99%
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24274-48-4 Name |
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Name |
CBDV |
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Synonym |
2-[(1R,6R)-3-Methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-propyl-1,3-benzenediol;Cannabidivarin;Cannabidivarol;Cannabidivarin solution;Cannabidivarin (CBDV);Cannabidivarin (CRM);Cannabidivarine;Cannabidivarol |
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24274-48-4 Chemical & Physical Properties |
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Boiling point |
439.4±45.0 °C(Predicted) |
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Density |
1.046±0.06 g/cm3(Predicted) |
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Molecular Formula |
C19H26O2 |
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Molecular Weight |
286.40900 |
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PSA |
40.46000 |
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LogP |
5.06630 |
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Exact Mass |
286.19300 |
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24274-48-4 Safety Information |
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Symbol |
GHS02, GHS06, GHS08 |
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Signal Word |
Danger |
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Hazard Statements |
H225-H301 + H311 + H331-H370-H412 |
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Precautionary Statements |
P210-P260-P273-P280-P301 + P310-P311 |
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RIDADR |
UN1230 - class 3 - PG 2 - Methanol, solution |
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Flash Point(F) |
48.2 °F |
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Flash Point(C) |
9 °C |
Physiological activity
Cannabidivarin, also known as cannabidivarol or CBDV, a structural analog of cannabidiol (CBD), has received attention in recent years owing to its anticonvulsant property and potential for treating autism spectrum disorder. As a natural analog of cannabidiol (CBD), nonpsychoactive cannabidivarin (CBDV) has therapeutic potential. CBDV also has antagonistic effects on diacylglycerol lipase-alpha and thus 2-arachidononyl glycerol.
InChI:InChI=1/C19H26O2/c1-5-6-14-10-17(20)19(18(21)11-14)16-9-13(4)7-8-15(16)12(2)3/h9-11,15-16,20-21H,2,5-8H2,1,3-4H3/t15-,16+/m1/s1
Cannabidivarin was safe but failed to reduce neuropathic pain in HIV-patients. Based on our findings, we do not recommend cannabidivarin as a treatment option for HIV-associated neuropathic pain.
Cannabidivarin (CBDV) is a propyl analogue of cannabidiol, a non-hallucinogenic phytocannabinoid. Fifty to ninety percent of children with RTT have epilepsy, which is often drug-resistant. Cannabidivarin (CBDV), a non-hallucinogenic phytocannabinoid, has shown benefit in MECP2 animal models.
2,4-dihydroxy-6-n-propylbenzoic acid, methyl ester
cannabidivarin
| Conditions | Yield |
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Multi-step reaction with 3 steps
1.1: boron trifluoride diethyl etherate / toluene / 20 °C
1.2: 0.42 h / 20 °C
2.1: potassium hydroxide / 2 h / 100 - 120 °C / 375.04 Torr
3.1: 150 °C
With boron trifluoride diethyl etherate; potassium hydroxide; In toluene;
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Multi-step reaction with 3 steps
1: sodium hydroxide / 2 h / 80 °C
2: boron trifluoride diethyl etherate; sodium hydrogencarbonate / acetonitrile / 0.58 h
3: sulfuric acid; potassium hydroxide / water; tert-butyl methyl ether / 40 - 150 °C
With sulfuric acid; boron trifluoride diethyl etherate; sodium hydrogencarbonate; potassium hydroxide; sodium hydroxide; In tert-butyl methyl ether; water; acetonitrile;
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Multi-step reaction with 3 steps
1: boron trifluoride diethyl etherate; sodium hydrogencarbonate / toluene / 1.42 h
2: potassium hydroxide / 2 h / 100 - 120 °C / 375.04 Torr
3: sulfuric acid; potassium hydroxide / water; tert-butyl methyl ether / 40 - 150 °C
With sulfuric acid; boron trifluoride diethyl etherate; sodium hydrogencarbonate; potassium hydroxide; In tert-butyl methyl ether; water; toluene;
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![(1'R,2'R)-3,5-dibromo-5'-methyl-2'-(prop-1-en-2-yl)-4-propyl-1',2',3',4'-tetrahydro-[1,1'-biphenyl]-2,6-diol](/upload/2023/1/106f5ecd-0982-4987-871d-b5a1285414d8.png)
(1'R,2'R)-3,5-dibromo-5'-methyl-2'-(prop-1-en-2-yl)-4-propyl-1',2',3',4'-tetrahydro-[1,1'-biphenyl]-2,6-diol
cannabidivarin
| Conditions | Yield |
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With triethylamine; sodium sulfite; ascorbic acid; In methanol; water; at 75 ℃; for 18h; Temperature;
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50% |
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With triethylamine; sodium sulfite; ascorbic acid; In methanol; water; at 75 ℃; for 24h;
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50% |
CBDVA
3,5-dimethoxybenzoyl chloride
3,5-dimethoxybenzoic acid
1,3-dimethoxy-5-propylbenzene
3-norpentyl-3-propyl-Δ8-tetrahydrocannabinol
(6aS,10aR)-6,6,9-trimethyl-3-propyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
tetrahydrocannabivarin
CBDVA
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