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987-65-5

  • Product Name:ATP-Na2, Adenosine 5'-triphosphate disodium salt
  • Molecular Formula:C10H14N5Na2O13P3
  • Appearance:Solid.
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Product Details

Appearance:Solid.

Purity:99%

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987-65-5 Name

Name

ATP-Na2

Synonym

 Adenosine 5’-triphosphate disodium salt,ADENOSINE TRIPHOSPHATE DISODIUM;ADENOSINE TRIPHOSPHATE, DISODIUM SALT;ADENYLPYROPHOSPHORIC ACID DISODIUM SALT;ADENOSINE-5'-TRIPHOSPHATE HYDRATE DISODIUM SALT;ADENOSINE-5'-TRIPHOSPHATE NA2-SALT;ADENOSINE-5'-TRIPHOSPHORIC ACID, DISODIUM;ADENOSINE-5'-TRIPHOSPHORIC ACID DISODIUM DIHYDROGEN SALT;ADENOSINE 5'-TRIPHOSPHORIC ACID DISODIUM SALT

 

987-65-5 Biological Activity

Related Catalog

Signaling Pathways >> Membrane Transporter/Ion Channel >> P2X Receptor

Natural Products >> Alkaloid

Research Areas >> Metabolic Disease

 

987-65-5 Chemical & Physical Properties

Melting point 

188-190ºC

Boiling point

951.4ºC at 760mmHg

Density

2.63g/cm3

Molecular Formula

C10H14N5Na2O13P3

Molecular Weight

551.145

PSA

314.22000

Exact Mass

550.959656

Water Solubility

H2O: 50 mg/mL

ATP-Na2 987-65-5 Powder Usage

Adenosine 5'-triphosphate disodium salt is a disodium salt form of adenosine-triphosphate which is a multifunctional nucleoside triphosphate. It is a multifunctional nucleoside triphosphate used in cells as a coenzyme of intracellular energy transfer. It transports chemical energy within cells for metabolism. ATP Disodium Salt is used in the synthetic preparation of ribose-modified deoxyadenosine bisphosphate analogues as P2Y1 receptor ligands. In some studies, adenosine 5'-triphosphate disodium salt hydrate (ATP-Na2) was used on the basis of the CI inhibition.

 

ATP-Na2 987-65-5 Relevant articles

Effects of ATP-MgCl2 and ATP-Na2 administration on renal function and cellular metabolism following renal ischemia.

Hirasawa H, Soeda K, Ohtake Y, Oda S, Kobayashi S, Odaka M, Sato H

Circulatory Shock, 01 Jan 1985, 16(4):337-346

The present study compared the effects of ATP-MgCl2 or ATP-Na2 administration on renal function and cellular metabolism following renal ischemia in rabbits. These results indicate that ATP should be given in the form of ATP-MgCl2 for it to be effective following renal ischemia. The results also suggest that the salutary effect of ATP-MgCl2 following renal ischemia could occur through the improvement of cellular metabolism and concomitant improvement in tissue blood flow.

A P(V)-N activation strategy for the synthesis of nucleoside polyphosphates

Sun, Qi,Gong, Shanshan,Sun, Jian,Liu, Si,Xiao, Qiang,Pu, Shouzhi

, p. 8417 - 8426 (2013/09/24)

A general and high-yielding synthesis of nucleoside 5′-triphosphates (NTPs) and nucleoside 5′-diphosphates (NDPs) from protected nucleoside 5′-phosphoropiperidates promoted by 4,5-dicyanoimidazole (DCI) has been developed. The experimental results suggested that the mechanism of DCI activation could be distinctive for NTP and NDP synthesis, depending on the different nucleophilicity of pyrophosphate and phosphate.

987-65-5 Process route

adenosine 5'-trimetaphosphate
53355-60-5

adenosine 5'-trimetaphosphate

adenosine 5'-triphosphate
606-67-7,987-65-5,4691-96-7,15237-44-2,20978-32-9,71997-34-7,71997-37-0,71997-53-0,71997-56-3

adenosine 5'-triphosphate

adenosine-5′-diphosphate trisodium salt
1172-42-5,2092-65-1,16178-48-6,20398-34-9,71997-33-6,71997-36-9,71997-52-9,71997-55-2

adenosine-5′-diphosphate trisodium salt

Conditions
Conditions Yield
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
 
adenosine 5′-phosphoropiperidate triethylammonium salt
1577254-51-3

adenosine 5′-phosphoropiperidate triethylammonium salt

adenosine 5'-triphosphate
606-67-7,987-65-5,4691-96-7,15237-44-2,20978-32-9,71997-34-7,71997-37-0,71997-53-0,71997-56-3

adenosine 5'-triphosphate

Conditions
Conditions Yield
adenosine 5′-phosphoropiperidate triethylammonium salt; With 4,5-dicyano-1H-imidazole; tris(tetra-n-butylammonium) hydrogen pyrophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 6h; Inert atmosphere;
With sodium acetate; In ethanol; water; Further stages; Inert atmosphere;
77%

987-65-5 Upstream products

  • 53355-60-5
    53355-60-5

    adenosine 5'-trimetaphosphate

  • 34051-17-7
    34051-17-7

    C10H12Cl2N5O5P

  • 58-61-7
    58-61-7

    adenosine

  • 7659-75-8
    7659-75-8

    adenosine (5'-phosphoro-1-piperidinide)

987-65-5 Downstream products

  • 1172-42-5
    1172-42-5

    adenosine diphosphate disodium salt

  • 61-19-8
    61-19-8

    5'-adenosine monophosphate

  • 58-64-0
    58-64-0

    adenosine 5'-diphosphate

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