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Appearance:white cryst. powder
Purity:99%
6020-87-7 Name |
|
Name |
Creatine monohydrate |
Synonym |
N-GUANYL-N-METHYLGLYCINE;N-GUANYL-N-METHYLGLYCINE, MONOHYDRATE;N-METHYL-N-GUANYLGLYCINE MONOHYDRATE;N-AMIDINOSARCOSINE;N-AMIDINOSARCOSINE HYDRATE;N-AMIDINOSARCOSINE MONOHYDRATE;Glycine, N-(aminoiminomethyl)-N-methyl-, monohydrate;jisuanyisui |
6020-87-7 Biological Activity |
|
Related Catalog |
Research Areas >> Metabolic Disease |
Target |
Human Endogenous Metabolite |
6020-87-7 Chemical & Physical Properties |
|
Melting point |
292 °C (dec.)(lit.) |
Molecular Formula |
C4H11N3O3 |
Molecular Weight |
149.148 |
PSA |
99.64000 |
Exact Mass |
149.080048 |
Storage condition |
Store at RT. |
Water Solubility |
13 g/L (20 ºC) |
Creatine Monohydrate is the monohydrate form of creatine similar or identical to endogenous creatine produced in the liver, kidneys, and pancreas. Pure creatine is a white, tasteless,odorless powder, that is a naturally occurring metabolite found in muscle tissue. Creatine is a natural compound made from the amino acids l-arginine, glycine, and methionine. Creatine has many benefits for health and performance. The most common is creatine monohydrate, a dietary supplement that improve strength, increase lean muscle mass, and help the muscles recover more quickly during exercise. It can also inhibit the generation of muscle fatigue factors, reduce fatigue and tension, restore physical fitness, accelerate protein synthesis in the human body, make muscles stronger, enhance muscle elasticity, reduce cholesterol, blood lipids, and blood sugar levels, improve middle-aged and elderly Muscular dystrophy, and delay aging.
InChI:InChI=1/C4H9N3O2/c1-7(4(5)6)2-3(8)9/h2H2,1H3,(H4,5,6,8,9)
The invention discloses a preparation method of creatine monohydrate, and provides the preparation method of the creatine monohydrate. The method is moderate in reaction condition, less in byproduct, high in yield and suitable for industrial production. The structure of the creatine monohydrate is as shown in the specification.
Substituted guanidine derivatives of the formula I, STR1 are prepared by reacting haloformamidinium salts of the formula II, STR2 where Hal can be Cl, F, Br and I, with primary or secondary amines of the formula III STR3 where the substituents R1 and R2 have the meanings explained in the description.
sarcosine
2-{[amino(imino)methyl]sulfanyl}acetic acid
creatine monohydrate powder
Conditions | Yield |
---|---|
at 60 ℃; for 3h;
|
80% |
CYANAMID
sodium sarcosinate
creatine monohydrate powder
Conditions | Yield |
---|---|
In water;
|
|
With water; at 20 - 80 ℃; for 1h; Temperature; Large scale;
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CYANAMID
sodium sarcosinate
sarcosine
2-{[amino(imino)methyl]sulfanyl}acetic acid
creatinine
Creatinine
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