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99-93-4

  • Product Name:4'-Hydroxyacetophenone
  • Molecular Formula:C8H8O2
  • Appearance:almost white to beige crystalline powder
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Product Details

Appearance:almost white to beige crystalline powder

Purity:99%

API 4'-Hydroxyacetophenone 99-93-4 Cheap Price

99-93-4 Name

Name

4'-Hydroxyacetophenone

Synonym

1-(4-hydroxyphenyl)-ethanon;4’-hydroxy-acetophenon;4-Hydroksyacetofenol;Acetophenone, p-hydroxy-;Ethanone, 1-(4-hydroxyphenyl)-;Hydroxyacetophenone, para;HYDROXYACETOPHENONE-4;HYDROXYBENZOPHENONE-4

 

99-93-4 Biological Activity

Related Catalog

Research Areas >> Infection

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

 

99-93-4 Chemical & Physical Properties

Melting point 

132-135 °C(lit.)

Boiling point

313.0±0.0 °C at 760 mmHg

Density

1.1±0.1 g/cm3

Molecular Formula

C8H8O2

Molecular Weight

136.148

Flash Point

121.2±12.4 °C

PSA

37.30000

LogP

1.42

Exact Mass

136.052429

Vapour Pressure

0.0±0.7 mmHg at 25°C

Index of Refraction

1.552

Storage condition

Refrigerator

Water Solubility

10 g/L (22 ºC)

API 4'-Hydroxyacetophenone 99-93-4  Usage

4'-hydroxyacetophenone (4-HAP) is a monohydroxyacetophenone carrying a hydroxy substituent at position 4'. It has a role as a plant metabolite, a fungal metabolite and a mouse metabolite. It has a good effect on yellow eyes caused by diseases such as hepatitis, and also has a good auxiliary effect on yellow eyes caused by various reasons. According to the classification provided by companies to ECHA in REACH registrations this substance causes serious eye irritation and is harmful to aquatic life with long lasting effects.

Definition

ChEBI: A monohydroxyacetophenone carrying a hydroxy substituent at position 4'.

IUPAC Standard InChI: InChI=1S/C11H16O2Si/c1-9(12)10-5-7-11(8-6-10)13-14(2,3)4/h5-8H,1-4H3

InChI version 1.06 IUPAC Standard

InChIKey: HVSXQEUGLVLBLR-UHFFFAOYSA-N

99-93-4 Relevant articles

A novel 4-hydroxyacetophenone monooxygenase featuring aromatic substrates preference for enantioselective access to sulfoxides

Shiyu Wei, Guochao Xu, Jieyu Zhou, Ye Ni

, Molecular Catalysis Volume 528, August 2022, 112496

The highest activities of HAPMOPf was 1.47 U·mg−1 toward 4-hydroxyacetophenone among tested ketone and thioether substrates. Furthermore, over 95% enantioselectivity was determined toward methyl phenyl sulfides with ortho, meta, and para-substituents (Cl, Br, CHO, NH2).

Decarboxylative Hydroxylation of Benzoic Acids

Ritter, Tobias,Su, Wanqi,Xu, Peng

supporting information, p. 24012 - 24017 (2021/10/06)

Herein, we report the first decarboxylative hydroxylation to synthesize phenols from benzoic acids at 35 °C via photoinduced ligand-to-metal charge transfer (LMCT)-enabled radical decarboxylative carbometalation. The aromatic decarboxylative hydroxylation is synthetically promising due to its mild conditions, broad substrate scope, and late-stage applications.

Development of pH-activatable fluorescent probes for rapid visualization of metastatic tumours and fluorescence-guided surgeryviatopical spraying

Cao, Wenwen,Li, Xiaoxin,Wu, Peng,Xiong, Hu

, p. 10636 - 10639 (2021/10/19)

We believe thatAzaB5is promising as a powerful tool to rapidly delineate a broad range of malignancies and assist surgical tumour resection.

99-93-4 Process route

1,2-bis(1-(4-methoxyphenyl)ethylidene)hydrazine
21399-34-8

1,2-bis(1-(4-methoxyphenyl)ethylidene)hydrazine

4-cyanophenol
767-00-0

4-cyanophenol

4-methoxybenzonitrile
874-90-8

4-methoxybenzonitrile

1-(4-methoxyphenyl)ethanone
100-06-1

1-(4-methoxyphenyl)ethanone

4-Hydroxyacetophenone
99-93-4

4-Hydroxyacetophenone

4-Methoxypropiophenone
121-97-1

4-Methoxypropiophenone

phenol
108-95-2,27073-41-2

phenol

Conditions
Conditions Yield
at 20 - 350 ℃; Product distribution;
45.7 % Chromat.
1.5 % Chromat.
0.8 % Chromat.
20.3 % Chromat.
1.7 % Chromat.
1.1 % Chromat.
1-methoxy-4-(1-methylethyl)benzene
4132-48-3

1-methoxy-4-(1-methylethyl)benzene

para-methoxynitrobenzene
100-17-4

para-methoxynitrobenzene

4-isopropyl-2-nitrophenol
1576-10-9

4-isopropyl-2-nitrophenol

4,6-di-isopropyl-2-nitrophenol
16928-17-9

4,6-di-isopropyl-2-nitrophenol

4-isopropyl-2-nitro-anisole
1706-61-2

4-isopropyl-2-nitro-anisole

1-(4-methoxyphenyl)ethanone
100-06-1

1-(4-methoxyphenyl)ethanone

4-Hydroxyacetophenone
99-93-4

4-Hydroxyacetophenone

Conditions
Conditions Yield
With nitric acid; 4-aminobenzene sulfonic acid; In sulfuric acid; at 25 ℃; Product distribution; Rate constant; various concentrations and molar ratios of HNO3 and H2SO4;
 

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