5-Bromoindole-2-carboxylic acid

Product Details

CasNo： 7254-19-5

Molecular Formula： C9H6BrNO2

Appearance： powder

Delivery Time： in stock

Throughput： 100|Kilogram|Day

Purity： 98% purity

Melting point     287-288
Boiling point     470.9±25.0 °C(Predicted)
density     1.838±0.06 g/cm3(Predicted)
storage temp.     -20°C
pka    4.25±0.30(Predicted)
form     Solid
CAS DataBase Reference    7254-19-5(CAS DataBase Reference)
Safety Information
Hazard Codes     Xi
Risk Statements     36/37/38
Safety Statements     26-37/39-36/37/39
WGK Germany     3
Hazard Note     Irritant
HazardClass     IRRITANT
HS Code     29339980
MSDS Information
Provider    Language
SigmaAldrich    English
5-Bromoindole-2-carboxylic acid Usage And Synthesis
Uses    5-Bromoindole-2-carboxylic acid,Reactant involved in studies of biologically active molecules including:Discovery of indole inhibitors of MMP-13 for treatment of arthritic diseases1;Synthesis of indolyl ethanones as indoleamine 2,3-dioxygenase inhibitors2 ;cis-Diaminocyclohexane derivatives prepared for use as factor Xa inhibitors3 ;Synthesis of tubulin polymerization inhibitors and cancer cell growth inhibitors4 ;Preparation of dual PPARγ/δ agonists5;Synthesis of chemical probes to examine the role of hFPRL1 receptor .
5-Bromoindole-2-carboxylic acid Preparation Products And Raw materials
Raw materials    Ethanol-->Polyphosphoric acid-->Ethyl pyruvate-->Lithium hydroxide-->4-BROMOPHENYLHYDRAZINE HYDROCHLORIDE
Preparation Products    2-(Ethoxycarbonyl)-5-bromo-indole-->5-Bromoindole-2-carboxylic acid methyl ester