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Appearance:powder
Throughput:100|Kilogram|Day
pd_productuse:intermediate
Delivery Time:in stock
Purity:98% purity
Melting point 287-288
Boiling point 470.9±25.0 °C(Predicted)
density 1.838±0.06 g/cm3(Predicted)
storage temp. -20°C
pka 4.25±0.30(Predicted)
form Solid
CAS DataBase Reference 7254-19-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39-36/37/39
WGK Germany 3
Hazard Note Irritant
HazardClass IRRITANT
HS Code 29339980
MSDS Information
Provider Language
SigmaAldrich English
5-Bromoindole-2-carboxylic acid Usage And Synthesis
Uses 5-Bromoindole-2-carboxylic acid,Reactant involved in studies of biologically active molecules including:Discovery of indole inhibitors of MMP-13 for treatment of arthritic diseases1;Synthesis of indolyl ethanones as indoleamine 2,3-dioxygenase inhibitors2 ;cis-Diaminocyclohexane derivatives prepared for use as factor Xa inhibitors3 ;Synthesis of tubulin polymerization inhibitors and cancer cell growth inhibitors4 ;Preparation of dual PPARγ/δ agonists5;Synthesis of chemical probes to examine the role of hFPRL1 receptor .
5-Bromoindole-2-carboxylic acid Preparation Products And Raw materials
Raw materials Ethanol-->Polyphosphoric acid-->Ethyl pyruvate-->Lithium hydroxide-->4-BROMOPHENYLHYDRAZINE HYDROCHLORIDE
Preparation Products 2-(Ethoxycarbonyl)-5-bromo-indole-->5-Bromoindole-2-carboxylic acid methyl ester
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